Herbalism is a traditional medicinal or folk medicine practice based on the use of plants and plant extracts. Herbalism is also known as botanical medicine, medical herbalism, herbal medicine, herbology, and phytotherapy. Sometimes the scope of herbal medicine is extended to include fungi and bee products, as well as minerals, shells and certain animal parts.

Many plants synthesize substances that are useful to the maintenance of health in humans and other animals. These include aromatic substances, most of which are phenols or their oxygen-substituted derivatives such as tannins. Many are secondary metabolites, of which at least 12,000 have been isolated — a number estimated to be less than 10% of the total. In many cases, these substances (particularly the alkaloids) serve as plant defense mechanisms against predation by microorganisms, insects, and herbivores. Many of the herbs and spices used by humans to season food yield useful medicinal compounds.

All plants produce chemical compounds as part of their normal metabolic activities. These include primary metabolites, such as sugars and fats, found in all plants, and secondary metabolites found in a smaller range of plants, some useful ones found only in a particular genus or species. Pigments harvest light, protect the organism from radiation and display colors to attract pollinators. Many common weeds have medicinal properties.

The functions of secondary metabolites are varied. For example, some secondary metabolites are toxins used to deter predation, and others are pheromones used to attract insects for pollination. Phytoalexins protect against bacterial and fungal attacks. Allelochemicals inhibit rival plants that are competing for soil and light.

Plants upregulate and downregulate their biochemical paths in response to the local mix of herbivores, pollinators and microorganisms.The chemical profile of a single plant may vary over time as it reacts to changing conditions. It is the secondary metabolites and pigments that can have therapeutic actions in humans and which can be refined to produce drugs.

Plants synthesize a bewildering variety of phytochemicals but most are derivatives of a few biochemical motifs.

Saturday 21 June 2008

Cat's Claw



Keywords: cat's claw, uña de gato, osteoarthritis, rheumatoid arthritis

Introduction
This fact sheet provides basic information about the herbA plant or part of a plant used for its flavor, scent, or potential therapeutic properties. Includes flowers, leaves, bark, fruit, seeds, stems, and roots. cat's claw—common names, uses, potential side effects, and resources for more information. Cat's claw grows wild in many countries of Central and South America, especially in the Amazon rainforest. The use of this woody vine dates back to the Inca civilization.

Common Names—cat's claw, uña de gato
Latin Names—Uncaria tomentosa, Uncaria guianensis


What It Is Used For
  1. Cat's claw has been used for centuries in South America to prevent and treat disease.
  2. It has been used for a variety of health conditions, including viral infections (such as herpes and HIV), Alzheimer's disease, cancer, and arthritis.
  3. Cat's claw has been used to support the immune system and promote kidney health, as well as to prevent and abort pregnancy.

How It Is Used
The inner bark of cat's claw is used to make liquid extracts, capsules, and teas. Preparations of cat's claw can also be applied to the skin.

What the Science Says
  • There is not enough scientific evidence to determine whether cat's claw works for any health problem, including arthritis, HIV, or cancer.
  • Small studies in humans have shown a possible benefit of cat's claw in osteoarthritis and rheumatoid arthritis, but no large trials have been done. In laboratory studies, cat's claw stimulates part of the immune system, but it has not been proven to reduce inflammation or boost the immune system in humans.
  • The National Institute on Aging is studying how cat's claw may affect the brain. Findings may point to new avenues for research in Alzheimer's disease treatment.

Side Effects and Cautions
  • Few side effects have been reported for cat's claw when it is taken at recommended dosages. Though rare, side effects may include headaches, dizziness, and vomiting.
  • Women who are pregnant or trying to become pregnant should avoid using cat's claw because of its past use for preventing and aborting pregnancy.
  • Because cat's claw may stimulate the immune system, it is unclear whether the herb is safe for people with conditions affecting the immune system.
  • Tell your health care providers about any complementary and alternative practices you use. Give them a full picture of what you do to manage your health. This will help ensure coordinated and safe care.

Sources
* Cat's claw. Natural Medicines Comprehensive Database Web site. Accessed on July 5, 2007.
* Cat's claw (Uncaria tomentosa, Uncaria guianensis). Natural Standard Database Web site. Accessed on July 3, 2007.

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